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  • 4 Similar Profiles
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Therapeutics Medicine & Life Sciences
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Pharmacology Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Derivatives Chemical Compounds
Cycloaddition Reaction Medicine & Life Sciences

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Projects 1977 2018

Optimization of HDAC6 Inhibitors in the Treatment of CMT

Kozikowski, A. P. & van Den Bosch, L.

4/1/133/31/18

Project: Research projectResearch Project

Optimizing Lead 5-HT2c Ligands for Use in the Treatment of Schizophrenia

Kozikowski, A. P., Wetsel, W., Roth, B. L., Caldarone, B. J. & Wardrop, D.

7/5/135/31/17

Project: Research projectResearch Project

Research Output 1973 2017

  • 18941 Citations
  • 69 h-Index
  • 518 Article
  • 2 Chapter
  • 2 Comment/debate
3 Citations

5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice

Pogorelov, V. M., Rodriguiz, R. M., Cheng, J., Huang, M., Schmerberg, C. M., Meltzer, H. Y., Roth, B. L., Kozikowski, A. P. & Wetsel, W. C. Apr 12 2017 (Accepted/In press) In : Neuropsychopharmacology.

Research output: Research - peer-reviewArticle

Serotonin
Schizophrenia
Antipsychotic Agents
Dopamine
Amphetamine
2 Citations

Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models

Ugolkov, A., Qiang, W., Bondarenko, G., Procissi, D., Gaisina, I., James, C. D., Chandler, J., Kozikowski, A., Gunosewoyo, H., O'Halloran, T., Raizer, J. & Mazar, A. P. Aug 1 2017 In : Translational Oncology. 10, 4, p. 669-678 10 p.

Research output: Research - peer-reviewArticle

Glycogen Synthase Kinase 3
Glioblastoma
Heterografts
Therapeutics
Neoplasms

Controlling extra- and intramacrophagic Mycobacterium abscessus by targeting mycolic acid transport

Viljoen, A., Herrmann, J. L., Onajole, O. K., Stec, J., Kozikowski, A. P. & Kremer, L. Sep 1 2017 In : Frontiers in Cellular and Infection Microbiology. 7, SEP, 388

Research output: Research - peer-reviewComment/debate

Mycolic Acids
Mycobacterium
Bacteria
Infection
Phagosomes
1 Citations

Design and Synthesis of Mercaptoacetamides as Potent, Selective, and Brain Permeable Histone Deacetylase 6 Inhibitors

Lv, W., Zhang, G., Barinka, C., Eubanks, J. H. & Kozikowski, A. P. May 11 2017 In : ACS Medicinal Chemistry Letters. 8, 5, p. 510-515 6 p.

Research output: Research - peer-reviewArticle

Histone Deacetylase Inhibitors
Prodrugs
Brain
Histone Deacetylases
Central Nervous System Diseases

Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications

Zhang, G., Cheng, J., McCorvy, J. D., Lorello, P. J., Caldarone, B. J., Roth, B. L. & Kozikowski, A. P. Jul 27 2017 In : Journal of Medicinal Chemistry. 60, 14, p. 6273-6288 16 p.

Research output: Research - peer-reviewArticle

Methylamines
Receptor, Serotonin, 5-HT2C
Serotonin Receptor Agonists
Antipsychotic Agents
Serotonin