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  • 4 Similar Profiles
Ligands Medicine & Life Sciences
Cocaine Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Pharmacology Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Derivatives Chemical Compounds
Protein Kinase C Medicine & Life Sciences

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Projects 1977 2018

Optimization of HDAC6 Inhibitors in the Treatment of CMT

Kozikowski, A. P. & van Den Bosch, L.

4/1/133/31/18

Project: Research projectResearch Project

Optimizing Lead 5-HT2c Ligands for Use in the Treatment of Schizophrenia

Kozikowski, A. P., Wetsel, W., Roth, B. L. & Caldarone, B. J.

7/5/135/31/17

Project: Research projectResearch Project

Design and Study of New Nicotinic Analogs for Use in Depression

Kozikowski, A. P.

8/10/095/31/16

Project: Research projectResearch Program--Cooperative Agreements

Chemistry and Biology of 5-HT2C Receptor Ligands for Drug Abuse

Kozikowski, A. P.

9/30/0712/31/13

Project: Research projectResearch Project

Research Output 1973 2017

  • 18702 Citations
  • 68 h-Index
  • 515 Article
  • 2 Chapter
  • 1 Comment/debate
2 Citations

5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice

Pogorelov, V. M., Rodriguiz, R. M., Cheng, J., Huang, M., Schmerberg, C. M., Meltzer, H. Y., Roth, B. L., Kozikowski, A. P. & Wetsel, W. C. Apr 12 2017 (Accepted/In press) In : Neuropsychopharmacology.

Research output: Research - peer-reviewArticle

Serotonin
Schizophrenia
Antipsychotic Agents
Dopamine
Amphetamine

Design and Synthesis of Mercaptoacetamides as Potent, Selective, and Brain Permeable Histone Deacetylase 6 Inhibitors

Lv, W., Zhang, G., Barinka, C., Eubanks, J. H. & Kozikowski, A. P. May 11 2017 In : ACS Medicinal Chemistry Letters. 8, 5, p. 510-515 6 p.

Research output: Research - peer-reviewArticle

Histone Deacetylase Inhibitors
Prodrugs
Brain
Histone Deacetylases
Central Nervous System Diseases

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function

Huang, J., Wang, L., Dahiya, S., Beier, U. H., Han, R., Samanta, A., Bergman, J., Sotomayor, E. M., Seto, E., Kozikowski, A. P. & Hancock, W. W. Dec 1 2017 In : Scientific Reports. 7, 1, 8626

Research output: Research - peer-reviewArticle

Histone Deacetylases
Allografts
Proteins
Transplantation
Histone Deacetylase Inhibitors

Molecular pathways: Revisiting glycogen synthase kinase-3β as a target for the treatment of cancer

Walz, A., Ugolkov, A., Chandra, S., Kozikowski, A., Carneiro, B. A., O'Halloran, T. V., Giles, F. J., Billadeau, D. D. & Mazar, A. P. Apr 15 2017 In : Clinical Cancer Research. 23, 8, p. 1891-1897 7 p.

Research output: Research - peer-reviewArticle

Glycogen Synthase Kinases
Neoplasms
Glycogen Synthase Kinase 3
Therapeutics
Protein-Serine-Threonine Kinases

Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models

Tavares, M. T., Shen, S., Knox, T., Hadley, M., Kutil, Z., Bařinka, C., Villagra, A. & Kozikowski, A. P. Oct 12 2017 In : ACS Medicinal Chemistry Letters. 8, 10, p. 1031-1036 6 p.

Research output: Research - peer-reviewArticle

Bearings (structural)
Histone Deacetylase Inhibitors
Histone Deacetylases
Tubulin
Scaffolds