Personal profile

Keywords

  • Neurodegneration
  • Neuroscience

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Apolipoproteins E Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Apolipoprotein E4 Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Amyloid beta-Peptides Medicine & Life Sciences
Apolipoprotein E3 Medicine & Life Sciences
Lipoproteins Medicine & Life Sciences

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Projects 1993 2019

Aged EFAD mice as a model for the effects of APOE and sex on AD pathology

Ladu, M. J.

National Institutes of Health

9/30/167/31/19

Project: Research projectExploratory/Developmental Cooperative Agreement Phase I

Alzheimer Disease
Pathology
Apolipoproteins E
Amyloid
Brain

TRANSFER OF MYOBLASTS EXPRESSING APOLIPOPROTEIN E

Ladu, M. J.

National Institutes of Health

10/28/93 → …

Project: Research projectPostdoctoral Individual National Research Service Award

Preclinical assessment of an ABCA1 agonist as a novel therapeutic for AD

Ladu, M. J.

National Institutes of Health

8/1/154/30/17

Project: Research projectExploratory/Developmental Grants

Alzheimer Disease
Apolipoprotein E4
Amyloid
Peptides
Apolipoproteins E

TLR4 antagonists as a therapeutic treatment for APOE-modulated neuroinflammation

Ladu, M. J.

9/1/145/31/16

Project: Research projectExploratory/Developmental Grants

Toll-Like Receptor 4
Alzheimer Disease
Amyloid
Neuroglia
Flavin-Adenine Dinucleotide
Amyloid beta-Peptides
Apolipoproteins E
Alzheimer Disease
Protein Isoforms
Pathology

Research Output 1985 2017

  • 5695 Citations
  • 39 h-Index
  • 73 Article
  • 3 Chapter
  • 2 Review article
  • 1 Comment/debate

APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease

Abdullah, L., Evans, J. E., Emmerich, T., Crynen, G., Shackleton, B., Keegan, A. P., Luis, C., Tai, L., LaDu, M. J., Mullan, M., Crawford, F. & Bachmeier, C. 2017 In : Aging. 9, 3, p. 964-985 22 p.

Research output: Contribution to journalArticle

Mild Cognitive Impairment
Docosahexaenoic Acids
Apolipoproteins E
Arachidonic Acid
Phospholipids
1 Citations

Rexinoids as therapeutics for alzheimer’s disease: Role of APOE

Koster, K. P., Smith, C., Valencia-Olvera, A. C., Thatcher, G. R. J., Tai, L. M. & LaDu, M. J. Mar 1 2017 In : Current Topics in Medicinal Chemistry. 17, 6, p. 708-720 13 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Apolipoprotein E4
Alleles
Retinoid X Receptors
Neurofibrillary Tangles
5 Citations

A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease

Luo, J., Lee, S. H., Vandevrede, L., Qin, Z., Ben Aissa, M., Larson, J., Teich, A. F., Arancio, O., D'Souza, Y., Elharram, A., Koster, K., Tai, L. M., Ladu, M. J., Bennett, B. M. & Thatcher, G. R. J. Apr 29 2016 In : Molecular Neurodegeneration. 11, 1, 35

Research output: Contribution to journalArticle

Alzheimer Disease
Pathology
Cyclic AMP Response Element-Binding Protein
Biological Markers
Mutation

APOE4 induces site-specific tau phosphorylation through calpain-CDK5 signaling pathway in EFAD-Tg mice

Zhou, M., Huang, T., Collins, N., Zhang, J., Shen, H., Dai, X., Xiao, N., Wu, X., Wei, Z., York, J., Lin, L., Zhu, Y., LaDu, M. J. & Chen, X. Sep 1 2016 In : Current Alzheimer Research. 13, 9, p. 1048-1055 8 p.

Research output: Contribution to journalArticle

Calpain
Phosphorylation
Alzheimer Disease
Amyloid
Genotype

Apolipoprotein e isotype-dependent modulation of microRNA-146a in plasma and brain

Teter, B., Ladu, M. J., Sullivan, P. M., Frautschy, S. A. & Cole, G. M. Aug 1 2016 In : NeuroReport. 27, 11, p. 791-795 5 p.

Research output: Contribution to journalArticle

Apolipoproteins
Apolipoproteins E
MicroRNAs
Brain
Apolipoprotein E4