Personal profile

Keywords

  • Neurodegneration
  • Neuroscience

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 11 Similar Profiles
Apolipoproteins E Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Apolipoprotein E4 Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Amyloid beta-Peptides Medicine & Life Sciences
Apolipoprotein E3 Medicine & Life Sciences
Lipoproteins Medicine & Life Sciences

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Projects 1993 2019

Aged EFAD mice as a model for the effects of APOE and sex on AD pathology

Ladu, M. J.

National Institutes of Health

9/30/167/31/19

Project: Research projectExploratory/Developmental Cooperative Agreement Phase I

Alzheimer Disease
Pathology
Apolipoproteins E
Amyloid
Brain

TRANSFER OF MYOBLASTS EXPRESSING APOLIPOPROTEIN E

Ladu, M. J.

National Institutes of Health

10/28/93 → …

Project: Research projectPostdoctoral Individual National Research Service Award

Preclinical assessment of an ABCA1 agonist as a novel therapeutic for AD

Ladu, M. J.

National Institutes of Health

8/1/154/30/17

Project: Research projectExploratory/Developmental Grants

Alzheimer Disease
Therapeutics
Apolipoprotein E4
Amyloid
Peptides

TLR4 antagonists as a therapeutic treatment for APOE-modulated neuroinflammation

Ladu, M. J.

9/1/145/31/16

Project: Research projectExploratory/Developmental Grants

Apolipoproteins E
Alzheimer Disease
Protein Isoforms
Amyloid beta-Peptides
Pathology

Research Output 1985 2017

  • 5800 Citations
  • 39 h-Index
  • 74 Article
  • 3 Chapter
  • 2 Review article
  • 1 Comment/debate
1 Citations

APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease

Abdullah, L., Evans, J. E., Emmerich, T., Crynen, G., Shackleton, B., Keegan, A. P., Luis, C., Tai, L., LaDu, M. J., Mullan, M., Crawford, F. & Bachmeier, C. 2017 In : Aging. 9, 3, p. 964-985 22 p.

Research output: Research - peer-reviewArticle

Docosahexaenoic Acids
Apolipoproteins E
Arachidonic Acid
Phospholipids
Alzheimer Disease
1 Citations

EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer's disease

Tai, L. M., Balu, D., Avila-Munoz, E., Abdullah, L., Thomas, R., Collins, N., Valencia-Olvera, A. C. & LaDu, M. J. 2017 In : Journal of Lipid Research. 58, 9, p. 1733-1755 23 p.

Research output: Research - peer-reviewArticle

Transgenic Mice
Alzheimer Disease
Pathology
Genotype
Therapeutic Human Experimentation
3 Citations

Rexinoids as therapeutics for alzheimer’s disease: Role of APOE

Koster, K. P., Smith, C., Valencia-Olvera, A. C., Thatcher, G. R. J., Tai, L. M. & LaDu, M. J. Mar 1 2017 In : Current Topics in Medicinal Chemistry. 17, 6, p. 708-720 13 p.

Research output: Research - peer-reviewReview article

Alzheimer Disease
Therapeutics
bexarotene
Apolipoprotein E4
Alleles
7 Citations

A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease

Luo, J., Lee, S. H., Vandevrede, L., Qin, Z., Ben Aissa, M., Larson, J., Teich, A. F., Arancio, O., D'Souza, Y., Elharram, A., Koster, K., Tai, L. M., Ladu, M. J., Bennett, B. M. & Thatcher, G. R. J. Apr 29 2016 In : Molecular Neurodegeneration. 11, 1, 35

Research output: Research - peer-reviewArticle

Alzheimer Disease
Therapeutics
Pathology
Pharmaceutical Preparations
Cyclic AMP Response Element-Binding Protein

APOE4 induces site-specific tau phosphorylation through calpain-CDK5 signaling pathway in EFAD-Tg mice

Zhou, M., Huang, T., Collins, N., Zhang, J., Shen, H., Dai, X., Xiao, N., Wu, X., Wei, Z., York, J., Lin, L., Zhu, Y., LaDu, M. J. & Chen, X. Sep 1 2016 In : Current Alzheimer Research. 13, 9, p. 1048-1055 8 p.

Research output: Research - peer-reviewArticle

Calpain
Phosphorylation
Alzheimer Disease
Amyloid
Genotype