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  • 5 Similar Profiles
Sickle Cell Anemia Medicine & Life Sciences
Pulmonary Hypertension Medicine & Life Sciences
Lung Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Mortality Medicine & Life Sciences
Pulmonary Artery Medicine & Life Sciences
Hemolysis Medicine & Life Sciences
Hemoglobins Medicine & Life Sciences

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Projects 2010 2019

Pulmonary Hypertension
sphingosine 1-phosphate
Smooth Muscle Myocytes

Vascular-targeted genomic and genetic strategies for acute chest syndrome

Machado, R.


Project: Research projectResearch Project

Use of Bosentan in Patients with Symptomatic PH Associat

Machado, R., Kato, G. & Gladwin, M. T.

Project: Research project

Research Output 1998 2017

1 Citations
Caveolin 1
Sequence Deletion
Pulmonary Hypertension
4 Citations

APOL1,α-thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia

Saraf, S. L., Shah, B. N., Zhang, X., Han, J., Tayo, B. O., Abbasi, T., Ostrower, A., Guzman, E., Molokie, R. E., Gowhari, M., Hassan, J., Jain, S., Cooper, R. S., Machado, R. F., Lash, J. P. & Gordeuk, V. R. 2017 In : Haematologica. 102, 1, p. e1-e6

Research output: Research - peer-reviewLetter

1 Citations

Association of circulating transcriptomic profiles with mortality in sickle cell disease

Desai, A. A., Lei, Z., Bahroos, N., Maienschein-Cline, M., Saraf, S. L., Zhang, X., Shah, B. N., Nouraie, S. M., Abbasi, T., Patel, A. R., Lang, R. M., Lussier, Y., Garcia, J. G. N., Gordeuk, V. R. & Machado, R. F. Jun 1 2017 In : Blood. 129, 22, p. 3009-3016 8 p.

Research output: Research - peer-reviewArticle

Sickle Cell Anemia
Acute Chest Syndrome

Hemin causes lung microvascular endothelial barrier dysfunction by necroptotic cell death

Singla, S., Sysol, J. R., Dille, B., Jones, N., Chen, J. & Machado, R. F. Sep 1 2017 In : American Journal of Respiratory Cell and Molecular Biology. 57, 3, p. 307-314 8 p.

Research output: Research - peer-reviewArticle

Cell Death
Cell death
Acute Chest Syndrome
Type II Bone Morphogenetic Protein Receptors
Endothelial Growth Factors
Caveolin 1
Transforming Growth Factor beta