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  • 5 Similar Profiles
Sickle Cell Anemia Medicine & Life Sciences
Pulmonary Hypertension Medicine & Life Sciences
Lung Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Mortality Medicine & Life Sciences
Pulmonary Artery Medicine & Life Sciences
Hemolysis Medicine & Life Sciences
Hemoglobins Medicine & Life Sciences

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Projects 2010 2019

Sphingolipids
Pulmonary Hypertension
sphingosine 1-phosphate
Smooth Muscle Myocytes
Lung

Vascular-targeted genomic and genetic strategies for acute chest syndrome

Machado, R.

2/5/131/31/18

Project: Research projectResearch Project

Use of Bosentan in Patients with Symptomatic PH Associat

Machado, R., Kato, G. & Gladwin, M. T.

Project: Research project

Research Output 1998 2017

1 Citations
Caveolin 1
Sequence Deletion
Adenine
Pulmonary Hypertension
Fibroblasts
4 Citations

APOL1,α-thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia

Saraf, S. L., Shah, B. N., Zhang, X., Han, J., Tayo, B. O., Abbasi, T., Ostrower, A., Guzman, E., Molokie, R. E., Gowhari, M., Hassan, J., Jain, S., Cooper, R. S., Machado, R. F., Lash, J. P. & Gordeuk, V. R. 2017 In : Haematologica. 102, 1, p. e1-e6

Research output: Research - peer-reviewLetter

1 Citations

Association of circulating transcriptomic profiles with mortality in sickle cell disease

Desai, A. A., Lei, Z., Bahroos, N., Maienschein-Cline, M., Saraf, S. L., Zhang, X., Shah, B. N., Nouraie, S. M., Abbasi, T., Patel, A. R., Lang, R. M., Lussier, Y., Garcia, J. G. N., Gordeuk, V. R. & Machado, R. F. Jun 1 2017 In : Blood. 129, 22, p. 3009-3016 8 p.

Research output: Research - peer-reviewArticle

Sickle Cell Anemia
Mortality
Testing
Blood
Acute Chest Syndrome

Hemin causes lung microvascular endothelial barrier dysfunction by necroptotic cell death

Singla, S., Sysol, J. R., Dille, B., Jones, N., Chen, J. & Machado, R. F. Sep 1 2017 In : American Journal of Respiratory Cell and Molecular Biology. 57, 3, p. 307-314 8 p.

Research output: Research - peer-reviewArticle

Hemin
Cell Death
Lung
Cell death
Acute Chest Syndrome
Type II Bone Morphogenetic Protein Receptors
Endothelial Growth Factors
Caveolin 1
Transforming Growth Factor beta
Inflammation