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  • 24 Similar Profiles
Mycobacterium tuberculosis Medicine & Life Sciences
Tuberculosis Medicine & Life Sciences
In Vitro Techniques Medicine & Life Sciences
Cerebellar Ataxia Chemical Compounds
Acids Medicine & Life Sciences
Cross Circulation Chemical Compounds
Structure-Activity Relationship Medicine & Life Sciences
Beryllium Chemical Compounds

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Projects 1988 2015

In vitro detection of anti-TB liver metabolites in early drug discovery

Franzblau, S. G.

National Institutes of Health

2/15/121/31/15

Project: Research projectExploratory/Developmental Grants

MSH Release-Inhibiting Hormone
Beryllium
Fibrin
Drug Discovery
Bibliography of Medicine

Lead identification of 1,4-benzoxazines as anti-tuberculosis agents

Franzblau, S. G.

National Institutes of Health

9/20/068/31/09

Project: Research projectExploratory/Developmental Grants

Benzoxazines
Tuberculosis
Lead
Macrophages
Cell Line
Antiviral Agents
Erythrasma
Beryllium
Buccal Administration
Blood Stains

Research Output 1983 2017

  • 10410 Citations
  • 49 h-Index
  • 333 Article
  • 1 Chapter

6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases

Thompson, A. M., Blaser, A., Palmer, B. D., Anderson, R. F., Shinde, S. S., Launay, D., Chatelain, E., Maes, L., Franzblau, S. G., Wan, B., Wang, Y., Ma, Z. & Denny, W. A. Jun 1 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 11

Research output: Contribution to journalArticle

Neglected Diseases
Thiazoles
Tuberculosis
Supravalvular Aortic Stenosis
Oxazoles

7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis

Thompson, A. M., O’Connor, P. D., Marshall, A. J., Yardley, V., Maes, L., Gupta, S., Launay, D., Braillard, S., Chatelain, E., Franzblau, S. G., Wan, B., Wang, Y., Ma, Z., Cooper, C. B. & Denny, W. A. May 25 2017 In : Journal of Medicinal Chemistry. 60, 10, p. 4212-4233 22 p.

Research output: Contribution to journalArticle

Oxazines
Antitubercular Agents
Visceral Leishmaniasis
Solubility
Safety

Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea

Velappan, A. B., Charan Raja, M. R., Datta, D., Tsai, Y. T., Halloum, I., Wan, B., Kremer, L., Gramajo, H., Franzblau, S. G., Kar Mahapatra, S. & Debnath, J. 2017 In : European Journal of Medicinal Chemistry. 125, p. 825-841 17 p.

Research output: Contribution to journalArticle

Mycolic Acids
Mycobacterium
Urea
Macrophages
Molecules
1 Citations

Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant: Mycobacterium tuberculosis

Lu, X., Hu, X., Liu, Z., Zhang, T., Wang, R., Wan, B., Franzblau, S. G. & You, Q. 2017 In : MedChemComm. 8, 6, p. 1303-1306 4 p.

Research output: Contribution to journalArticle

Hydrazones
Mycobacterium tuberculosis
Amides
Extensively Drug-Resistant Tuberculosis
Lead
1 Citations

Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum

Gomes, M. N., Alcântara, L. M., Neves, B. J., Melo-Filho, C. C., Freitas-Junior, L. H., Moraes, C. B., Ma, R., Franzblau, S. G., Muratov, E. & Andrade, C. H. Jun 1 2017 In : Bioorganic and Medicinal Chemistry Letters. 27, 11

Research output: Contribution to journalArticle

Leishmania infantum
Chalcone
Leishmania
Association Learning
Supravalvular Aortic Stenosis