A case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation

Manami Oguri, Takako Tachikawa, Yuko Kamei, Tatsuya Mimura, Masao Matsubara

Research output: Contribution to journalArticle

Abstract

Purpose: To report a case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation.Case: A 73-year-old woman presented with left esotropia since 2 months before. She had received surgery for cholangiocarcinoma 5 months before. Findings and Clinical Course: Corrected visual acuity was 1.2 right and 0.6 left. The left eye showed persistent esotropia by 60Δ. Contrast-enhanced magnetic resonance imaging (MRI) showed a metastatic tumor mass in the suprasellar region. Multiple lesions developed during the following one month, including blepharoptosis, dysarthria, and headache. Stereotactic radiotherapy was performed. Generalized metastasis developed, resulting in death 10 months after her initial consultation. Conclusion: The present case illustrates that cerebral tumor or angioma may be the cause in acutely impaired ocular motility. Contrast MRI is indicated in the presence of history of malignancy.

Original languageEnglish (US)
Pages (from-to)515-521
Number of pages7
JournalJapanese Journal of Clinical Ophthalmology
Volume71
Issue number4
StatePublished - Apr 1 2017

Fingerprint

Esotropia
Cholangiocarcinoma
Paralysis
Magnetic Resonance Imaging
Neoplasm Metastasis
Neoplasms
Blepharoptosis
Dysarthria
Hemangioma
Visual Acuity
Headache
Radiotherapy
Referral and Consultation

ASJC Scopus subject areas

  • Ophthalmology

Cite this

A case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation. / Oguri, Manami; Tachikawa, Takako; Kamei, Yuko; Mimura, Tatsuya; Matsubara, Masao.

In: Japanese Journal of Clinical Ophthalmology, Vol. 71, No. 4, 01.04.2017, p. 515-521.

Research output: Contribution to journalArticle

Oguri, Manami; Tachikawa, Takako; Kamei, Yuko; Mimura, Tatsuya; Matsubara, Masao / A case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation.

In: Japanese Journal of Clinical Ophthalmology, Vol. 71, No. 4, 01.04.2017, p. 515-521.

Research output: Contribution to journalArticle

@article{ef11ad54f3594149b1fd4ec3a2b11e79,
title = "A case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation",
abstract = "Purpose: To report a case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation.Case: A 73-year-old woman presented with left esotropia since 2 months before. She had received surgery for cholangiocarcinoma 5 months before. Findings and Clinical Course: Corrected visual acuity was 1.2 right and 0.6 left. The left eye showed persistent esotropia by 60Δ. Contrast-enhanced magnetic resonance imaging (MRI) showed a metastatic tumor mass in the suprasellar region. Multiple lesions developed during the following one month, including blepharoptosis, dysarthria, and headache. Stereotactic radiotherapy was performed. Generalized metastasis developed, resulting in death 10 months after her initial consultation. Conclusion: The present case illustrates that cerebral tumor or angioma may be the cause in acutely impaired ocular motility. Contrast MRI is indicated in the presence of history of malignancy.",
author = "Manami Oguri and Takako Tachikawa and Yuko Kamei and Tatsuya Mimura and Masao Matsubara",
year = "2017",
month = "4",
volume = "71",
pages = "515--521",
journal = "Japanese Journal of Clinical Ophthalmology",
issn = "0370-5579",
publisher = "Igaku-Shoin Ltd",
number = "4",

}

TY - JOUR

T1 - A case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation

AU - Oguri,Manami

AU - Tachikawa,Takako

AU - Kamei,Yuko

AU - Mimura,Tatsuya

AU - Matsubara,Masao

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Purpose: To report a case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation.Case: A 73-year-old woman presented with left esotropia since 2 months before. She had received surgery for cholangiocarcinoma 5 months before. Findings and Clinical Course: Corrected visual acuity was 1.2 right and 0.6 left. The left eye showed persistent esotropia by 60Δ. Contrast-enhanced magnetic resonance imaging (MRI) showed a metastatic tumor mass in the suprasellar region. Multiple lesions developed during the following one month, including blepharoptosis, dysarthria, and headache. Stereotactic radiotherapy was performed. Generalized metastasis developed, resulting in death 10 months after her initial consultation. Conclusion: The present case illustrates that cerebral tumor or angioma may be the cause in acutely impaired ocular motility. Contrast MRI is indicated in the presence of history of malignancy.

AB - Purpose: To report a case of cerebral metastasis of cholangiocarcinoma with abducens palsy as the initial manifestation.Case: A 73-year-old woman presented with left esotropia since 2 months before. She had received surgery for cholangiocarcinoma 5 months before. Findings and Clinical Course: Corrected visual acuity was 1.2 right and 0.6 left. The left eye showed persistent esotropia by 60Δ. Contrast-enhanced magnetic resonance imaging (MRI) showed a metastatic tumor mass in the suprasellar region. Multiple lesions developed during the following one month, including blepharoptosis, dysarthria, and headache. Stereotactic radiotherapy was performed. Generalized metastasis developed, resulting in death 10 months after her initial consultation. Conclusion: The present case illustrates that cerebral tumor or angioma may be the cause in acutely impaired ocular motility. Contrast MRI is indicated in the presence of history of malignancy.

UR - http://www.scopus.com/inward/record.url?scp=85020251239&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85020251239&partnerID=8YFLogxK

M3 - Article

VL - 71

SP - 515

EP - 521

JO - Japanese Journal of Clinical Ophthalmology

T2 - Japanese Journal of Clinical Ophthalmology

JF - Japanese Journal of Clinical Ophthalmology

SN - 0370-5579

IS - 4

ER -